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The Supraketo Fat Burner-fueled brain: unnatural or advantageous? Disclaimer: First things first. Please note that I am in no way endorsing nutritional ketosis as a supplement to, or a replacement for medication. Join Our Community of Science Lovers! Disclaimer: First things first. Please note that I am in no way endorsing nutritional ketosis as a supplement to, or a replacement for medication. ’t yet know the side effects of a long-term ketogenic diet. This post talks about the SCIENCE behind ketosis, and is not meant in any way as medical advice. The ketogenic diet is a nutritionist’s nightmare. High in saturated fat and VERY low in carbohydrates, "keto" is adopted by a growing population to paradoxically promote weight loss and mental well-being. Drinking coffee with butter? Eating a block of cream cheese? Little to no fruit? To the uninitiated, Supraketo Official Site keto defies all common sense, inviting skeptics to wave it off as an unnatural "bacon-and-steak" fad diet.

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today. Yet versions of the ketogenic diet have been used to successfully treat drug-resistant epilepsy in children since the 1920s - potentially even back in the biblical ages. Emerging evidence from animal models and clinical trials suggest keto may be therapeutically used in many other neurological disorders, including head ache, neurodegenerative diseases, sleep disorders, bipolar disorder, autism and brain cancer. With no apparent side effects. Sound too good to be true? I feel ya! Where are these neuroprotective effects coming from? What’s going on in the brain on a ketogenic diet? In essence, a ketogenic diet mimics starvation, allowing the body to go into a metabolic state called ketosis (key-tow-sis). Normally, Supraketo Keto Pills Fat Burner human bodies are sugar-driven machines: ingested carbohydrates are broken down into glucose, which is mainly transported and used as energy or stored as glycogen in liver and muscle tissue.

20% of total energy expenditure. The brain cannot DIRECTLY use fat for energy. Once liver glycogen is depleted, without a backup energy source, humanity would’ve long disappeared in the eons of evolution. The backup is ketone bodies that the liver derives primarily from fatty acids in your diet or body fat. These ketones - ? "energy factory" mitochondria and used up as fuel. Excess BHB and acetoacetate are excreted from urine, while acetone, due to its volatile nature, is breathed out (hence the characteristically sweet "keto breath"). Meanwhile, blood glucose remains physiologically normal due to glucose derived from certain amino acids and the breakdown of fatty acids - voila, low blood sugar avoided! So the brain is happily deriving energy from ketones - sure, but why would this be protective against such a variety of brain diseases? One answer may be energy. Despite their superficial differences, many neurological diseases share one major problem - deficient energy production.

During metabolic stress, ketones serve as an alternative energy source to maintain normal brain cell metabolism. In fact, BHB (a major ketone) may be an even more efficient fuel than glucose, providing more energy per unit oxygen used. A ketogenic diet also increases the number of mitochondria, so called "energy factories" in brain cells. A recent study found enhanced expression of genes encoding for mitochondrial enzymes and energy metabolism in the hippocampus, a part of the brain important for learning and memory. Hippocampal cells often degenerate in age-related brain diseases, leading to cognitive dysfunction and memory loss. With increased energy reserve, neurons may be able to ward off disease stressors that would usually exhaust and kill the cell. A ketogenic diet may also DIRECTLY inhibit a major source of neuronal stress, by -well- acting like a blueberry. Reactive oxygen species are unfortunate byproducts of cellular metabolism. Unlike the gas Oxygen, these "oxidants" have a single electron that makes them highly reactive, bombarding into proteins and membranes and wrecking their structure.

Increased oxidants are a hallmark of aging, stroke and neurodegeneration. Ketones directly inhibit the production of these violent molecules, and enhance their breakdown through increasing the activity of glutathione peroxidase, a part of our innate anti-oxidant system. The low intake of carbohydrates also directly reduces glucose oxidation (something called "glycolysis"). Using a glucose-like non-metabolized analogue, one study found that neurons activate stress proteins to lower oxidant levels and stabilize mitochondria. Due to its high fat nature, keto increases poly-unsaturated fatty acids (PUFAs, such as DHA and EPA, both sold over-the-counter as "brain healthy" supplements), which in turn reduces oxidant production and inflammation. Inflammatory stress is another "root of all evil", which PUFAs target by inhibiting the expression of genes encoding for pro-inflammatory factors. Neurons on Ketones: Dampen that enthusiasm! Excited neurons transmit signals, process information and Supraketo Fat Burner form the basis of a functioning brain. OVER-excited neurons tend to die. The brain teeters on a balance between excitation and inhibition through two main neurotransmitters, the excitatory glutamate and the inhibitory GABA.